Search results for "Organ function"
showing 4 items of 4 documents
A case of naturally evolving gout in an elderly man
2012
Gout is a common disorder in adults that can lead to severe organ decline, disability and impaired quality of life due to the formation of periarticular tophi. We report a case of massive tophaceous gout in a 78-year-old man with a 16-year-long history of untreated disease. The patient gradually became disabled, his renal function deteriorated, and he finally died of sepsis. Our case demonstrates that chronic gout not only affects the joints, but is also associated with organ function decline and can, even nowadays, lead to death. © 2011 Elsevier Ireland Ltd.
Basic Mechanisms of Diffusive and Diffusion-Related Oxygen Transport in Biological Systems: A Review
1992
In mammals, energy metabolism of active tissues requires permanent availability of oxygen. Because cessation of O 2 supply results in loss of organ function within seconds or minutes, continual feed of adequate amounts of O 2 to tissue is the most vital task for living organisms. For many years, it therefore has been one of the greatest challenges to physiologists to understand the mechanisms provided by nature to satisfy this need for oxygen.
Intensive Care Management of Head-Injured Patient
2019
Traumatic brain injury (TBI) plays an important role for the prognosis of multiple injured patients. Severely injured patients require intensive care treatment to support organ function and to maintain normal brain physiology. Optimal treatment is a cornerstone for good outcome. Therefore, in addition to general principles and concepts of modern intensive care medicine, special brain-specific aspects need to be addressed in these patients. Essential aspects of physiological regulation of cerebral perfusion and intracranial pressure as well as recent publications are reviewed as basis for current trends in the management of TBI patients. Focusing on single parameters such as intracranial pre…
Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences
2019
Abstract Background A central topic is to bring traditional medicine to a new horizon by integrating the latest advances in genomic, metabolomic, and system biological approaches, in order to re-examine the wisdom and knowledge of traditional Chinese medicine (TCM) and other traditional medicines. Purpose A new consortium has been formed at a conference of the Harvard Medical School, Boston, on October 29–30, 2018. The main goal was to build a collaborative platform for the scientific investigation of traditional medicine with cutting edge sciences and technologies at the forefront of biomedicine. Results Traditional medicines are largely experience-based, but the scientific basis is largel…